| Identifiers | ||
| Product Name | SBE Reporter Kit (TGFβ/SMAD signaling pathway) | |
| Catalogue No. | CM902050 | |
| Description | The SBE Reporter kit is designed for monitoring the activity of TGFβ/SMAD signaling pathway in the cultured cells. The kit contains transfection-ready SBE luciferase reporter vector, which is a TGFβ pathway-responsive reporter. This reporter contains a firefly luciferase gene under the control of multimerized SBE responsive element located upstream of a minimal promoter. The SBE reporter is premixed with constitutively-expressing Renilla luciferase vector that serves as internal control for transfection efficiency. The kit also includes a non-inducible firefly luciferase vector premixed with constitutively-expressing Renilla luciferase vector as negative control. The noninducible luciferase vector contains a firefly luciferase gene under the control of a minimal promoter, without any additional response elements. The negative control is critical to determining pathway-specific effects and background luciferase activity. | |
| Application | • Monitor TGFβ signaling pathway activity. • Screen for activators or inhibitors of the TGFβ/ SMAD signaling pathway. • Study effects of RNAi or gene overexpression on the activity of the TGFβ pathway. |
|
| Product Type | Reporter Assay Kit | |
| Host | HEK293 | |
| Storage Condition | refer to Technology Column | |
| Brand | Packing | Pricing | Quote request |
| IL | 500 reactions | Inquiry | Ask Quote |
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