Identifiers | ||
Product Name | NaV1.8/β1–HEK293 Recombinant Human Stable Cell Line | |
Catalogue No. | CM902042 | |
Description | Nav1.8 is a voltage gated type X, alpha subunit sodium channel which in humans is encoded by the SCN10A gene. It is expressed in nociceptors and has been proposed as a target for the development of new analgesics [1]. Mice deficient in Nav1.8 have deficits in sensing inflammatory pain (initiated by tissue damage/inflammation) and visceral pain (initiated by damage or injury to internal organs) but not neuropathic pain. Native sodium channels are complexes composed of the pore-forming subunit and an auxiliary subunit. The sodium channel beta 1 subunit, encoded by the SCN1B gene, increases current amplitude and surface expression of sodium ion channels. | |
Product Type | Cell Line | |
Host | HEK293 | |
Source Antibody | human | |
Storage Condition | liquid N2 |
Brand | Packing | Pricing | Quote request |
IL | 2x10(6) cells | Inquiry | Ask Quote |
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