| Identifiers | ||
| Product Name | WNT TCF/LEF reporter kit | |
| Catalogue No. | CM902031 | |
| Description | The TCF/LEF Reporter kit is designed for monitoring the activity of Wnt / β-catenin signaling pathway in the cultured cells. The kit contains transfection-ready TCF/LEF luciferase reporter vector, which is a Wnt pathway-responsive reporter. This reporter contains a firefly luciferase gene under the control of multimerized TCF/LEF responsive element located upstream of a minimal promoter. The TCF/LEF reporter is premixed with constitutively-expressing Renilla luciferase vector that serves as internal control for transfection efficiency. The kit also includes a non-inducible firefly luciferase vector premixed with constitutively-expressing Renilla luciferase vector as negative control. The non-inducible luciferase vector contains a firefly luciferase gene under the control of a minimal promoter, without any additional response elements. The negative control is critical to determining pathway specific effects and background luciferase activity. | |
| Application | • Monitor Wnt /β-catenin signaling pathway activity. • Screen for activators or inhibitors of the Wnt /β-catenin signaling pathway. • Study effects of RNAi or gene overexpression on the activity of the Wnt /β-catenin pathway. |
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| Product Type | Reporter Assay Kit | |
| Storage Condition | refer to Technology Column | |
| Brand | Packing | Pricing | Quote request |
| IL | 500 reactions | Inquiry | Ask Quote |
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