| Identifiers | ||
| Product Name | Tubastatin A hydrochloride, HDAC inhibitor | |
| Catalogue No. | CM901526 | |
| Description | Tubastatin A is a potent HDAC6 inhibitor. It demonstrates over 1,000-fold selectivity against all other HDAC isoforms (IC50 >16 µM), excluding HDAC8 (IC50 = 0.9 µM). Tubastatin A induces a-tubulin hyperacetylation at 2.5 µM in primary cortical neuron cultures. In a model of oxidative stress induced by glutathione depletion, it displays dose-dependent neuronal protection of primary cortical neuron cultures at 5-10 µM. | |
| CAS Number | 1310693-92-5 | |
| Formula | C20H21N3O2• HCl | |
| MW | 371.9 Da | |
| Product Type | Inhibitor | |
| Grade | ≥98% by HPLC. | |
| Storage Condition | refer to Technology Column | |
| Brand | Packing | Pricing | Quote request |
| IL | 10 mg | Inquiry | Ask Quote |
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