| Identifiers | ||
| Product Name | YM201636 | |
| Catalogue No. | CM860127 | |
| Description | Cell-permeable. YM-201636 is a selective inhibitor of phosphoinositide kinase (PIK) PIKfyve (IC50 = 33 nM). It inhibits p110α at higher concentration (IC50 = 3 µM). It reversibly impairs endosomal trafficking in NIH3T3 cells, mimicking the effect produced by depleting PIKfyve with siRNA.YM-201636 also blocks retroviral exit by budding from cells. | |
| CAS Number | 371942-69-7 | |
| Formula | C₂₅H₂₁N₇O₃ | |
| MW | 467.49 | |
| Grade | ≥98% by NMR | |
| Storage Condition | -20°C | |