Identifiers |
|
Product Name |
YC-1 |
Catalogue No. |
CM860126 |
Description |
Cell-permeable. A nitric oxide (NO) independent, superoxide-sensitive soluble guanylyl cyclase (sGC) activator (EC₅₀ = 18 µM). Induces concentration-dependent increase in cGMP levels in cultured cells and in rabbit aortic rings. Inhibits platelet adhesion to collagen. A non-specific phosphodiesterase (PDE) inhibitor. YC-1 also inhibits HIF-α activity in tumors resulting in blocked angiogenesis and an inhibition of tumor growth. Inhibits Na⁺ channel. |
CAS
Number |
170632-47-0 |
Formula |
C₁₉H₁₆N₂O₂ |
MW |
304.34 |
Grade |
≥98% by NMR |
Storage
Condition |
-20°C |