Identifiers |
|
Product Name |
S-Adenosyl-L-methionine disulfate tosylate |
Catalogue No. |
CM860081 |
Description |
A methyl donor and a cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver where 85% of all methylation reactions occur. SAM is anti-apoptotic in normal hepatocytes and normal colon epithelial cells but pro-apoptotic in liver human hepatocellular carcinoma (HCC), HepG2 cells and colon cancer cells. |
CAS
Number |
97540-22-2 |
Formula |
C₁₅H₂₂N₆O₅S.C₇H₁₂O₁₁S₂ |
MW |
766.8 |
Grade |
≥95% by HPLC |
Storage
Condition |
-20°C |