| Identifiers | ||
| Product Name | Flavopiridol | |
| Catalogue No. | CM860001 | |
| Description | Cell-permeable. Flavopiridol is a synthetic flavonoid compound used as an anticancer agent. It is a serine/threonine kinase inhibitor that broadly targets cyclin-dependent kinases (CDKs), including the cyclin 9/cyclin T complex (pTEF-b), preventing activation of RNA polymerase II. Flavopiridol initiates cell cycle arrest and p53-independent apoptosis through down-regulation of Mcl-1 and X-linked inactivator of apoptosis (XIAP). | |
| CAS Number | 146426-40-6 | |
| Formula | C₂₁H₂₀ClNO₅ | |
| MW | 401.84 | |
| Grade | ≥98% by HPLC | |
| Storage Condition | -20°C | |