| Identifiers | ||
| Product Name | Bromodomain Inhibitor, (+)-JQ1 | |
| Catalogue No. | CM859953 | |
| Description | Cell-permeable. A potent and highly specific inhibitor for the BET (bromodomain and extra-terminal) family of bromodomains. (+)-JQ1 binds to BRD4 bromodomains 1 and 2 with Kd values of ~ 50 and 90 nM, respectively. The binding is competitive with acetyl lysine. (+)-JQ1 can be a useful chemical probe to investigate the role of BET bromodomains in the transcriptional regulation of oncogenesis. | |
| CAS Number | 1268524-70-4 | |
| Formula | C₂₃H₂₅ClN₄O₂S | |
| MW | 456.99 | |
| Grade | ≥98% by HPLC | |
| Storage Condition | -20°C | |