Identifiers |
|
Product Name |
Fludarabine Phosphate |
Catalogue No. |
CM816939 |
Description |
A chemotherapy drug used in the treatment of hematological malignancies. Fludarabine phosphate is rapidly dephosphorylated to 2-fluoro-ara-A and then phosphorylated intracellularly by deoxycytidine kinase to the active triphosphate, 2-fluoro-ara-ATP. This metabolite may inhibit DNA polymerase-⍺, ribonucleotide reductase and DNA primase, thereby interrupting DNA synthesis and inhibiting tumor cell growth. |
CAS
Number |
75607-67-9 |
Formula |
C₁₀H₁₃FN₅O₇P |
MW |
365.21 |
Storage
Condition |
-20°C |