Identifiers | ||
Product Name | GW2580 | |
Catalogue No. | CM816917 | |
Description | A small-molecule, ATP-competitive inhibitor of cFMS kinase; at 60 nM it inhibits human cFMS kinase completely in vitro and was inactive against 26 other kinases. GW2580 also inhibits lipopolysaccharide (LPS)-induced TNF production in mice, but not LPS-induced TNF production in freshly isolated human monocytes and mouse macrophages in vitro. | |
CAS Number | 870483-87-7 | |
Formula | C₂₀H₂₂N₄O₃ | |
MW | 366.41 | |
Storage Condition | -20°C |