Identifiers | ||
Product Name | Lactacystin (Synthetic) | |
Catalogue No. | CM816902 | |
Description | Cell-permeable. A potent and selective inhibitor of the 20 S proteasome. Binds irreversibly to the active site N-terminal threonine residue of the catalytic β-subunit of the 20S proteasome, thereby inhibiting its chymotrypsin and trypsin-like activities. Induces neurite outgrowth in Neuro 2A neuroblastoma cells and has been reported to induce apoptosis in human monoblast U937 cells. Also inhibits NF-kB activation (IC₅₀ = 10 µM). | |
CAS Number | 133343-34-7 | |
Formula | C₁₅H₂₄N₂O₇S | |
MW | 376.42 | |
Storage Condition | -20°C |
Brand | Packing | Pricing | Quote request |
IL | 200 ug | Inquiry | Ask Quote |
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