| Identifiers | ||
| Product Name | NF-kB reporter (Luc) - HEK293 Cell line | |
| Catalogue No. | CM802643 | |
| Description | The NF-κB reporter (luc)-HEK293 cell line is designed for monitoring the nuclear factor Kappa B (NF-κB) signal transduction pathways. It contains a firefly luciferase gene driven by four copies of NF-κB response element located upstream of the minimal TATA promoter. After activation by pro-inflammatory cytokines or stimulants of lymphokine receptors, endogenous NF-κB transcription factors bind to the DNA response elements, inducing transcription of the luciferase reporter gene. | |
| Application | The NF-κB reporter cell line is designed for screening inhibitors of NF-κB and for monitoring NF-κB signaling pathway activity. | |
| Product Type | Cell Line | |
| Host | HEK293 | |
| Source Antibody | human | |
| Storage Condition | refer to Technology Column | |