| Identifiers | ||
| Product Name | A 83-01 | |
| Catalogue No. | CM726671 | |
| Description | A selective inhibitor of TGF-β type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 (IC₅₀ values are 12, 45 and 7.5 nM respectively). Blocks phosphorylation of Smad2 and inhibits TGF-β-induced epithelial-to-mesenchymal transition. Helps maintain homogeneity and long-term in vitro self-renewal of human induced pluripotent stem cells (iPSCs). | |
| Application | 1 mg. Purity:>98% by HPLC. CAS1 909910-43-6. A selective inhibitor of TGF-β type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 (IC50 values are 12, 45 and 7.5 nM respectively). Blocks phosphorylation of Smad2 a | |
| CAS Number | 909910-43-6 | |
| Formula | C₂₅H₁₉N₅S | |
| MW | 421.52 | |
| Storage Condition | -20°C | |
| Brand | Packing | Pricing | Quote request |
| IL | 1 mg | Inquiry | Ask Quote |
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