Identifiers | ||
Product Name | Galanin Receptor GalR1 | |
Catalogue No. | CM525757 | |
Description | GalR1 is a Galanin Receptor that mediates the effects of the peptide galanin in a wide variety of tissues. Unlike GalR2, the primary signaling mechanism of GalR1 is by inhibiting adenylate cyclase through Gi. GalR1 regulates the GnRH neuroendocrine axis with its expression in POMC neurons. Pathogens like E. coli can cause diarrhea by increasing expression of Galanin Receptor 1 in the epithelial cells lining the colon, resulting in increased secretion of colonocyte chloride and fluid. GalR1 has been reported in brain, spinal cord, small intestine, colon, and eye. ESTs have been isolated from nerve and fetal lung/testis/B-cell libraries. | |
Host | Rabbit | |
Storage Condition | Long term: -70°C; Short term: -4°C |
Brand | Packing | Pricing | Quote request |
IL | 50 ul | Inquiry | Ask Quote |
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