| Identifiers |
 |
| Product Name |
L-JNK Peptide Inhibitor I |
| Catalogue No. |
CM261710 |
|
Description |
A protein inhibitor named JIP-1/IB1 has been described that competitively blocks the interaction between JNK and c-Jun, thereby inhibiting the signaling events downstream of JNK, like c-Jun, ATF-2 and ELK1 phosphorylation. To convert JIP-1/IB-1 into cell permeable inhibitors of JNK (JNKI1) the minimal 20 amino acids inhibitory sequence of JIP-1/IB1 was covalently linked to the 10 amino acids recognized by TAT transporter. The L-JNKI1 is a potent inhibitor that is specific for JNK and can be used for in vitro applications. |
|
Application |
50 ul (1 mM) JNK peptide inhibitor. It is ready-to-use and cell permeable. It can be used in 1000X dilutions. |
| Formula |
C₁₆₄H₂₈₆N₆₆O₄₀ |
| MW |
3822.5 |
| Storage
Condition |
-20°C |