| Identifiers |
 |
| Product Name |
G418 Sulfate |
| Catalogue No. |
CM260614 |
|
Description |
Aminoglycoside antibiotic related to gentamycin that inhibits prokaryotic and eukaryotic protein synthesis. Toxic to bacteria, yeast, protozoans, helminths, higher plant, and mammalian cells. Widely used in the selection of eukaryotic expression vectors carrying the bacterial neor/kanr genes. The product of these genes, aminoglycoside 3′-phosphotransferase, inactivates G418, neomycin, and kanamycin by phosphorylation. Introduction of either of these genes into cells can confer resistance to G418, which enables cells to grow in media containing G418. |
|
Application |
1 g; Purity:>98%; CAS1 108321-42-2; The effective killing concentration of this antibiotic will vary as to the cell type, media, growth conditions, and the cells metabolic rate and position in the cell cycle. Effective concentrations range from 100 µg/ml |
| CAS
Number |
108321-42-2 |
| Formula |
C₂₀H₄₀N₄O₁₀. 2 H₂SO₄ |
| MW |
692.71 |
| Grade |
≥98% |
| Storage
Condition |
RT |